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Remedied The Disease: He then learned that a diet rich in fresh milk, meat, and, most especially, yeast, remedied the disease, presumably by sup¬plying a nutritional factor, which Goldberger called the P-P factor. This factor, now known as niacin, or nicotinic acid, is a member of the vitamin B complex group.
Thus, this kind of heart disease has been practically eradicated, al¬though rare cases are still encountered in elderly people. Other endocrine disorders affecting the heart are very rare.
Congenital Heart Disease. With the increasing control of rheumatic heart disease it is probable that congenital cardiovascular disease will soon outstrip it in incidence, and with the increasing control of high blood pressure, congenital heart disease will take second place. An interesting statistical fact is that in the 1920's, T. Duckett Jones and Paul Dudley White found that con¬genital heart disease made up only 1.5% of all of 3,000 patients with Signs or symptoms of heart disease.See Also Uncommon Disease Caused:GRANULOMA INGUINALE, gran-ya-lo'ma ing-gwi-na'le, is a relatively uncommon disease caused by the bacterium Donovania granulomatis, also called the "Donovan body." Granuloma in-guinale is believed to be transmitted during sexual intercourse, and its communicability seems to be low.
Although most of the causes of heart disease observed in the first quarter of the 20th century are still present, their relative proportions have changed considerably, and some causes that were mentioned only occasionally or not at all at that time are considered common today. This is espe¬cially true of the virus infections. In some parts of the world the diagnosis of "heart disease of unknown origin" is a common one. In the United States such a diagnosis exists but is uncommon, and a few kinds of heart disease that are com¬mon in certain other countries are rare or non¬existent in the United States. For example, Chagas' disease (myocardial trypanosomiasis) is a parasitic infestation of the heart common in South America.
On The Other Hand See Glom-erulonephritis—the Disease That:The serum was administered for four postoperative months in accordance with techniques derived from previous animal experiments. ALS was also used without other drugs for a short preoperative period. Of the 20 patients, 19 survived; the 20th died from glom-erulonephritis—the disease that had originally afflicted his own kidneys—and not from any aftereffect of the transplant operation.
Since coronary heart disease has become a leading cause of death in young and middle-aged men in the United States and since there is no really effective cure for it, either surgical or medical, it is essential that the causes of the disease be appraised so that preventive measures can be devised. Studies show that several factors are involved in coronary heart disease, with no single cause being entirely responsible, but the degree of responsibility of each of the many causes is not known. |
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