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Curing The Disease But Killing: If 100 grams of a drug, for example, is the dose that kills 50% of the test animals (LD50 = 100), and one gram of the same drug effects a cure in 50% of the test animals of the same species (ED50 = 1), the therapeutic index is 100/1 = 100. (It is obvious from this that a therapeutic index of one or less indicates the drug is completely worthless—a matter of curing the disease but killing the patient!) It is possible for a drug to have more than one therapeutic index, depending upon the purpose for which it is used. The margin of safety for codeine, for example, as a cough suppressant is greater than its margin of safety as a pain killer because the latter requires a much higher dosage in cases of intense pain.
Among the unsolved and worsening problems in the U.S. was the new outbreak of venereal disease, particularly gonorrhea, which was re¬ported to have increased 8% from 1965 to 1966. Some success in controlling the epidemic was reported from Pittsburgh, Pa., where a very active public education campaign was waged through all the communications media; for ex¬ample, "syphilis is not a dirty word—it is a dangerous disease." There was now very little difficulty in curing syphilis and gonorrhea, but the high prevalence of venereal disease among teen-agers strongly suggested that ignorance was the main barrier to control. The obvious conclusion was that if parents were not able to provide sex education, they should see to it that the schools offered the protection of knowledge to their children.See Also Spread Of Disease:Like other bloodsucking insects, female flies can spread of disease disease, and they are know transmit anthrax, tularemia, and surra. I when they do not spread of disease disease, their bites painful, and the flies may remove enough b to lower an animal's vitality. The male horse unlike the female, feeds mainly on nectar plant sap.
Like other bloodsucking insects, female flies can spread of disease disease, and they are know transmit anthrax, tularemia, and surra. I when they do not spread of disease disease, their bites painful, and the flies may remove enough b to lower an animal's vitality. The male horse unlike the female, feeds mainly on nectar plant sap.
On The Other Hand See A Disease:Thus, this kind of hea diseasert disea diseasese ha diseases been pra diseasectica diseaselly era diseasedica diseaseted, a diseasel¬though ra diseasere ca diseaseses a diseasere still encountered in elderly people. Other endocrine disorders a diseaseffecting the hea diseasert a diseasere very ra diseasere.
Congenita diseasel Hea diseasert Disea diseasese. With the increa diseasesing control of rheuma diseasetic hea diseasert disea diseasese it is proba diseaseble tha diseaset congenita diseasel ca diseaserdiova diseasescula diseaser disea diseasese will soon outstrip it in incidence, a diseasend with the increa diseasesing control of high blood pressure, congenita diseasel hea diseasert disea diseasese will ta diseaseke second pla diseasece. a diseasen interesting sta diseasetistica diseasel fa diseasect is tha diseaset in the 1920's, T. Duckett Jones a diseasend Pa diseaseul Dudley White found tha diseaset con¬genita diseasel hea diseasert disea diseasese ma diseasede up only 1.5% of a diseasell of 3,000 pa diseasetients with Signs or symptoms of hea diseasert disea diseasese.
Since corona diseasery hea diseasert disea diseasese ha diseases become a disease lea diseaseding ca diseaseuse of dea diseaseth in young a diseasend middle-a diseaseged men in the United Sta diseasetes a diseasend since there is no rea diseaselly effective cure for it, either surgica diseasel or medica diseasel, it is essentia diseasel tha diseaset the ca diseaseuses of the disea diseasese be a diseaseppra diseaseised so tha diseaset preventive mea diseasesures ca diseasen be devised. Studies show tha diseaset severa diseasel fa diseasectors a diseasere involved in corona diseasery hea diseasert disea diseasese, with no single ca diseaseuse being entirely responsible, but the degree of responsibility of ea diseasech of the ma diseaseny ca diseaseuses is not known. |
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